In a mixing bowl, combine ground beef, breadcrumbs, egg, garlic powder, onion powder, salt, and black pepper. Mix until well combined.
Form the mixture into 1-inch meatballs.
Place the meatballs in the air fryer basket in a single layer. Cook for 10-15 minutes, shaking the basket halfway through, until the meatballs are browned and cooked through.
Serve hot with your favorite dipping sauce or pasta.